BDGP Information

BDGP in Brief

The Berkeley Drosophila Genome Project (BDGP) is a consortium of the Drosophila Genome Center, funded by the National Human Genome Research Institute, National Cancer Institute, and Howard Hughes Medical Institute, through its support of work in the Gerald Rubin, Allan Spradling, Roger Hoskins, Hugo Bellen, Susan Celniker, and Gary Karpen laboratories.

The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community.

The work of the Drosophila Genome Center is performed in the laboratory of Gerald Rubin in the Dept. of Molecular and Cell Biology at the University of California, Berkeley (cDNA project, P element insertion project, informatics); at the Lawrence Berkeley National Laboratory in Berkeley, CA, with co-directors Gerald Rubin and Susan Celniker (genomic sequencing; cDNA project), as well as the labs of Roger Hoskins and Gary Karpen (P disruption project); in the laboratory of Allan Spradling at the Carnegie Institution of Washington, in Baltimore, MD (P element insertion project); and the laboratory of Hugo Bellen at the Baylor College of Medicine, in Houston, TX (P disruption project). Part of the BDGP Informatics Group is a member of the FlyBase consortium.